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ACSS2 enables melanoma cell survival and tumor metastasis by negatively regulating the Hippo pathway

Laundon, D., Gostling, N

J Pineal Res 49(1):7885 Abdelmegeed MA et al (2012) Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced non-alcoholic steatohepatitis

& Shoubridge, E

For example, a phase I clinical study revealed that ascorbate concentrations could safely reach 25-30 mM with intravenous infusion of 100 g of vitamin C

Several studies have shown that cyclophosphamide markedly elevated expression of the pro-apoptotic proteins: p53, Bax and caspase3 enzyme besides the markedly reduced expression of the anti-apoptotic protein BCL-2 [23, 25, 62, 63]