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Factor V Leiden an overview ScienceDirect Topics Multifactorial Inheritance and Gene Environment Interactions Medical Genetics 1st Ed Factor V Leiden thrombophilia is the most common inherited cause of hypercoagulability. It is caused by a point mutation in factor V which renders it resistant to degradation by protein C. Learn Factor V Leiden and Venous Thrombosis Objectives CDC For exam focus on Classic Five inherited thrombophilias 1. Factor V Leiden mutation 2. Prothrombin (Factor II) mutation 3. Protein C deficiency 4. Protein S deficiency 5. Antithrombin III deficiency Factor V Leiden
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