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Effects of continuous infusions (10 days) and cessation of infusions of clonidine and rilmenidine (S 3341) on cardiovascular and behavioral parameters of spontaneously hypertensive rats

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The following experimental conditions were applied: CE mode: CZE Electrolyte: Phosphate, pH 1.8 (adjusted with phosphoric acid (85 %) to fulfill the SST) Capillary: fused silica, 75 m ID, 64.5 cm total length Temperature: 25C Injection: 5 s, 50 mbar Detection: direct UV, 200 nm Separation: 20 kV Description: The method is used for testing the purity of glutathione by determining the related substances L-cysteinylglycine, L-cysteine, L-glutathione oxidized, L-y-glutamyl-L-cysteine and unspecified impurities

Ethics declarations Ethics approval and consent to participate The study was conducted in accordance with the Declaration of Helsinki, and approved by the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine (Guangzhou, China) (JY2024-149 10/23/2024)

IV solutions are compounded by a licensed pharmacy for individual use under healthcare professional oversight and are not Health Canada-approved marketed drugs

Wichtig: Die folgenden Informationen beschreiben Dosen, die in verffentlichten klinischen Studien zu Cagrilintid verwendet wurden