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Finisguerra V, Di Conza G, Di Matteo M, Serneels J, Costa S, Thompson AA, et al

Research shows that eight weeks of SS-31 treatment in aged mice completely reversed age-related declines in exercise tolerance, with treated aged animals achieving treadmill endurance performance comparable to young controls

After deprotonation of the other, non-attacking Sec/Cys residue the mixed disulphide is resolved, resulting in the release of reduced hTrx1

10.1038/sj.embor.7400248 214 TrinchieriG

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