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Many in vitro experiments under different experimental conditions confirmed the good antioxidant activity of melatonin, however, levels of melatonin in certain body organs might not be high enough to exhibit antioxidant properties (Sanchez-Barcelo et al

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The production of these antibodies may be related to gut microbiota dysbiosis and increased intestinal permeability ( 2 The microbiota-gut-brain axis and schizophrenia: evidence from clinical and preclinical studies During fetal development, microbial communities are already present in the maternal placenta, amniotic fluid, and umbilical cord ( In recent years, numerous clinical studies have demonstrated that patients with schizophrenia exhibit characteristic gut dysbiosis, manifested as significant disruptions in microbial relative abundance and reduced -diversity ( Proteobacteria and Lactobacillus , along with decreased levels of anti-inflammatory commensals such as Prevotella ( Lachnoclostridium and reduced levels of short-chain fatty acid-producing Blautia spp