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The absorption of light by chromophores puts them in a state of high excitation marked by a tendency to undergo rapid chemical reactions with other molecules, including molecular oxygen, which can lead to the production of ROS 3,4,21

Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

433 Specifically, alcohol-dependent rats were administered semaglutide, which resulted in a significant reduction in their alcohol consumption

Glutamate release assay The release of intracellular glutamate into the extracellular medium was quantified using the Amplex Red Glutamic Acid/Glutamate Oxidase Assay Kit (Invitrogen, A12221) following the manufacturers protocol

doi: 10.1038/sj.mp.4001888 314 MockingRJAssiesJLokARuheHGKoeterMWVisserIet al