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GSH levels were enriched in the TIF compared with serum in mouse models of cancer and in human patients with cancer

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Many experimental studies have shown that female mice are less susceptible to APAP hepatotoxicity than males and that the sex differences are substantial [17,18,35]

In macrophages, the knockdown of SIRT1 has been shown to increase the activation levels of NF-B and pro-inflammatory cytokines [343]

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