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The effects of melatonin are mediated by two types of G-protein-coupled receptors (MT1 and MT2) located in various parts of the brain and peripheral tissues, such as the liver, pancreatic and cells, adrenal glands, blood vessels, and gonads [75]

Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia

(85) confirmed this observation, reporting significantly higher BCAAs in PCOS patients (540.59 97.23 nmol/mL vs 501.09 85.33 nmol/mL), particularly in those exhibiting HA

Most CRC cases are sporadic and progress from adenoma to carcinoma through multiple genetic and epigenetic alterations (Song et al., 2020)

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Vitamin A supports ocular surface repair and maintenance (Samarawickrama et al., 2015), and Vitamins C and E, both potent antioxidants, help alleviate symptoms of DED by reducing oxidative stress (Huang et al., 2016)