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ROS-sensitive Crocin-loaded chitosan microspheres for lung targeting and attenuation of radiation-induced lung injury

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Simultaneously, it alleviates oxidative stress by activating the Nrf2 antioxidant pathway, indirectly breaking the vicious cycle of mutual exacerbation between inflammation and oxidative damage, synergistically enhancing the protective effect against periodontitis ( Silybin can exert anti-inflammatory effects in skin diseases, ocular diseases, and oral diseases by regulating signaling pathways such as NF-B and AP-1, modulating immune cells, and other mechanisms, thereby alleviating tissue damage and improving disease-related symptoms ( Table 6 )

It has a favorable safety profile and provides symptomatic improvement for moderate-to-severe HS patients

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