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Interestingly, glycolytic enzymes expression has also been reported to be decreased in an animal at the advanced stage of HF [142], suggesting that global alteration of glucose catabolic processes takes part in the collapse of cardiomyocyte energy metabolism and in the energetic distress of the failing myocardium

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Vzquez MJ, Novelle MG, Rodrguez-Pacheco F, Lage R, Varela L, Lpez M et al

Under resting conditions, Ca2+ enters the intermembrane space through voltage-dependent anion channels located on the outer mitochondrial membrane

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Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity