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PMID 17584130

Alternative to Traditional Medications

Melanin does not block enough UV to make sun time safe. Using less SPF is one of the fastest ways to stack damage, even if you do not see a burn

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Smith et al 29 demonstrated that DHA is cytotoxic to melanoma cells through reaction oxygen species (ROS) generation, mitochondrial dysfunction, G 2 /M cell cycle phase arrest, and apoptotic cell death

Phase II trials in healthy volunteers used 0.16 mg/kg subcutaneous injections with dose-dependent skin darkening (Barnetson et al., 2006)