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[ 24 , 25 ] Since it interacts with the dopaminergic system, it can make certain opioids like morphine less efficient

However, with direct injection, if you do not need the additional B12, it may result in high levels in your blood that can cause side effects including gastrointestinal issues, headache and dizziness, tiredness and weakness, or skin irritation until the excess is flushed out via your kidneys and urine

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