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Two components contribute to CAI

Handling & Storage Store according to established laboratory practices appropriate for peptide materials

Following the standard titration schedule significantly reduces severity

BPCDX, fabricated in a good manufacturing practices (GMP)-certified clean room according to stringent quality processes, was tested to evaluate optical and mechanical properties, enzymatic degradation and cell compatibility and underwent a panel of third-party certified medical device tests compliant with ISO standards to assess biocompatibility, toxicity, carcinogenicity, sensitization and irritation using in vitro and in vivo assays in mice, guinea pigs and rabbits

Headline points: Both compounds independently produce dose-related nausea, vomiting, constipation, and decreased appetite

In some embodiments, the otic pharmaceutical formulation comprises about 68% by weight of the triglycerides