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The phenylacetyl modification addresses this challenge by creating a compound that resists degradation while crossing cell membranes more effectively than standard reduced glutathione

Positive regulators of ferroptosis increase the sensitivity of PCa cells to docetaxel, indicating that triggering ferroptosis could be a promising approach for treating CRPC

Brain Res 1131 : 1728

One such drug is the antiarrhythmic lidocaine, which has a bioavailability of only 3% when taken orally (see Chapter 12, Local Anesthetic Pharmacology)

"'Bioavailable' means the amount of a nutrient that gets absorbed and used by the body