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Paralllement, il rgule l'activit des mtalloprotinases matricielles (MMP) et de leurs inhibiteurs (TIMP), permettant un remodelage contrl de la matrice extracellulaire

In addition, amygdalin was shown to increase Bax and decrease Bcl-2 expression in SK-BR-3 and MCF-7 breast cancer cells

However, CD3 CAR T cells of LTR exhibited significantly increased mTOR and pS6 expression compared to STR, suggesting a shift from a memory-to-effector metabolic phenotype of LTR CAR T cells from pre- to post-infusion, respectively (Fig