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doi: 10.1111/j.1440-1819.2010.02079.x 71 MorrisGPuriBKBortolasciCCCarvalhoABerkMWalderKet al

Cell 138(3):562575

Cardoso BR, Busse AL, Hare DJ et al (2016) Pro198Leu polymorphism affects selenium status and GPx activity in response to Brazil nut intake

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however, these oral uses are limited by their side effects, such as nausea, diarrhoea, and headaches, and inhaled drugs have proven ineffective so far

These ROS can directly damage epithelial cells and extracellular matrix, leading to ulceration and propagating inflammation