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each case is judged individually.11 Solid evidence on the safety of parenteral, lifelong, high dose hydroxocobalamin is available from decades of treating patients with inborn errors of B 12 metabolism (eg, cobalamin C deficiency).6768 Symptom monitoring Monitor symptoms regularly (eg, every two to three months) as they may reappear, even after several months, if injection frequency is reduced

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Initial treatment for a vitamin B12 deficiency may involve injections of hydroxocobalamin every other day for two weeks or until symptoms improve

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If a vial accidentally freezes, discard it rather than attempting to use it after thawing

This radial movement simultaneously pushes the cartridge plunger within the medication chamber, causing the medication to be injected into patients body through a disposable needle in a precise and accurate way