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Contact Us IGF-1 LR3 (Long Arg3-IGF-1) is a synthetic 83-amino-acid analogue of insulin-like growth factor 1, engineered with an N-terminal 13-amino-acid extension and an Arg3 substitution that together confer markedly reduced affinity for IGF-binding proteins (IGFBPs) and extended plasma half-life

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For the sake of data purity in a research setting, we recommend avoiding all calories during the fasting window

References Int J Mol Sci (MDPI) Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties (2025) PMC/Biogerontology Epitalon increases telomere length in human cell lines through telomerase upregulation Neuroendocrinology Letters (PubMed) Synthetic tetrapeptide Epitalon restores neuroendocrine regulation in senescent monkeys Bull Exp Biol Med (PubMed) Geroprotective effect of epithalamine in elderly with accelerated aging (12-year RCT) Alzheimer's Drug Discovery Foundation Epithalamin/Epitalon Cognitive Vitality Report (mechanisms, dosing, safety) JPT Peptide Technologies Peptide Stability: How Long Do Peptides Last

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An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]