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However, it can also occur in dark-skinned individuals and, as described above, similar lesions can arise in places that are never exposed to the sun

doi:10.1038/s41598-018-19445-4 Svart M, Gormsen LC, Hansen J, Zeidler D, Gejl M, Vang K, Aanerud J, Moeller N (2018) Regional cerebral effects of ketone body infusion with 3-hydroxybutyrate in humans: reduced glucose uptake, unchanged oxygen consumption and increased blood flow by positron emission tomography

Breed Susceptibility and Genetic Predispositions Certain breeds are more susceptible to joint issues

Together, these data reinforce the model that KG and carnitine are upstream of histone acetylation to drive resistance to DNA-damaging agents directly