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[312] Consumption of coffee and tea, particularly 2-3 cups of coffee and more than 4 cups of tea per day, is associated with increased macular retinal nerve fiber layer (mRNFL) thickness, suggesting potential neuroprotective effects that warrant further investigation into causal links and mechanisms

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Its deficiency has been linked to impaired social behavior and heightened anxiety-like symptoms in children with ASD (Pivina et al., 2019)

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In 2009 such defects were found to cause abnormal cytoskeletal rearrangement, leading to abnormal cell structure, defective migration and adhesion causing an autosomal recessive combined immunodeficiency

Recently, non-covalent inhibitors of SmTGR, presenting antischistosomal efficacy in an animal model of infection, were developed targeting the doorstop pocket (here site S3), which further validates this pocket as a druggable site 96