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Meng, Z., Qiu, Y., Lin, K

Intracellular LPO generation BODIPY581/591-C11 (Thermo Fisher), a fluorescent probe for LPO detection that can insert into lipid membranes and been oxidized by intracellular LPO, was used to assess the intracellular LPO level

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Discussion Radiogenomics in hematologic malignancies The rule is, not to besiege walled cities if it can possibly be avoided - The Art of War , Sun Tzu While successful efforts in non-hematologic malignancies have linked radiation sensitivity to genomic classifiers for solid tumors, implicating genes like KEAP1 and CTNNB1 and pathways such as ROS reduction and cell-cycle deregulation, these studies have often explicitly omitted hematologic malignancies (162)

Furthermore, epigenetic alterations, including DNA methylation, histone modification and non-coding RNAs expression, not only modify Atgs but also affect signaling genes, thus inhibiting or promoting of autophagy (35) (Fig

The presence of necrotic tissue together with apoptosis is consistent with defective efferocytosis in human plaques