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Association between immune-related adverse events and clinical efficacy in patients with melanoma treated with nivolumab: a multicenter retrospective study

JZha: Writing original draft, Visualization, Software, Funding acquisition, Formal analysis, Data curation, Resources, Methodology, Conceptualization, Project administration, Writing review & editing, Validation, Investigation, Supervision

A three-year study of patients receiving regular Epithalon courses observed no adverse effects in the treatment group, with significantly reduced mortality compared to control groups

Pyroptosis, another mode of cell death, is triggered by inflammatory vesicles and is characterized by the discharge of substantial quantities of proinflammatory cytokines, such as IL-18 and IL-1

Glutamate transport Glutamate transport is coupled to the cotransport of three Na + ions and one H + ion with the counter transport of one K + ion and is linked to an uncoupled Cl anion current

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