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Stockholm Convention on Persistent Organic Pollutants

However, when delivered as a zinc oxide-sulfasalazine nanoparticle derivative, it has better tumor retention with improved cytotoxic effects and no evident damage to healthy cells (135)

This is crucial for maintaining the sterility and safety of the solution over its refrigerated lifespan

Those in the N-acetylcysteine group did not experience any adverse events

O'Dwyer PJ, Hamilton TC, LaCreta FP, Gallo JM, Kilpatrick D, Halbherr T, Brennan J, Bookman MA, Hoffman J, Young RC, Comis RL, Ozols RF: Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer