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Eshraghian M

J Thorac Cardiovasc Surg 170(2):359-368.e3, 2025

B.HongJ

Mimicking IVD Structure The IVD is composed of a central NP surrounded by an AF and upper and lower hyaline cartilage endplates

In miRNA point of view, research shows that Treatment with genistein led to a significant inhibition of cell proliferation, as measured by MTT assay, and induced apoptosis while on the molecular level genistein downregulated the expression of miR-95, a microRNA implicated in cancer progression, as well as the mRNA levels of Akt and SGK1, two serine/threonine kinases known to promote survival and proliferation in cancer cells