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Kohansal R, Martinez-Camblor P, Agust A, et al

The Effects of Rare SERPINA1 Variants on Lung Function and Emphysema in SPIROMICS. American Journal of Respiratory and Critical Care Medicine, vol

Dissociated TXNIP combines with and activates the NLRP3 inflammasome to induce IL-1 expression in a NLRP3-ASC-caspase-1-dependent manner, thus causing inflammatory reactions