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Pharmacology 61 , 154166 (2000)

Description Epithalon Peptide 10mg (Lyophilized Peptide) For Research Use Only Epithalon (also known as Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the naturally occurring pineal gland peptide Epithalamin

However, there is no definitive evidence of efficacy in humans, and its status remains investigational pending rigorous clinical research

The resulting IL-6/sIL-6R complex can activate gp130 on nearly all cell types, including those that do not express mIL-6R, thereby dramatically broadening the cellular targets of IL-6

Wu, H., Liu, X., Jaenisch, R

Assuming oral bioavailability of ~1% with current formulations that have been FDA-approved compared to injections of the same peptide, the cost-of-goods argument becomes unsustainable for most candidates that might be considered for conversion to the oral route