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The diminished proliferation of gsh2 mutants which are non-melanized and have reduced susceptibility to phagocytosis in the brain of infected mice affirms critical roles for melanin and phagocytic uptake in dissemination (via survival in host macrophages, which can enhance virulence 41 ), traversal of the blood-brain barrier, and neurotropism 7

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Compared to young mice, aged mice displayed a significant decrease in the PB1 extrusion rate and the number of ovulated oocytes, accompanied by a significant increase in the number of fragmented and dead oocytes (Fig

Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis