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This may pose a potential risk to some patients ( seeWARNINGSandPRECAUTIONS, Drug Interactions)

In ophthalmic clinical trials (RGN-259), the topical thymosin beta-4 formulation was well tolerated, with no serious adverse effects attributable to the treatment

NSun2, a noncoding RNA methyltransferase (which requires methyl group from SAM) was reported to be reduced in post-mortem AD brain tissue

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