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Rather, mutations affecting the dimerization interfaces of the G6PD protein and in proximity to the NADP + binding site may cause more detrimental effects compared to mutations of residues in other less conserved sites

The metabolic state in PD effluent could tell how healthy the membrane is and how long it will survive

MonelliFVenturelliFBonilauriLManicardiEManicardiVRossiPGet al

Moreover, it was unclear at the time which cellular phenotypes correspond to either primary or secondary effects due to the lack of FXN

Markers of lipid and DNA oxidative damage have been detected in several CNS cells, including neurons, axons, myelin, and OLs in early active lesions with the highest levels of expression in cells that morphologically resembled apoptotic OLs [10,11]

Tal como se usa en el presente documento, un sitio de glicosilacin no nativo se refiere a una posicin amino a la cual el resto de hidrato de carbono se une en un polipptido modificado que no est presente en un polipptido natural