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Heffernan 2001a Mouse studies using chronic osmotic pump delivery showed AOD-9604 increased fat oxidation and plasma glycerol (a lipolysis marker) to a degree comparable with full-length hGH, without inducing hyperglycaemia or reducing insulin secretion

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Adding AOD-9604 might bring that total to 7-8.5 kg, with the additional loss coming predominantly from fat tissue rather than lean mass

D-Nle-Tyr-Ile-NH-(CH 2 ) 5 - CONH 2 appeared to be extensively distributed outside the central blood compartment and/or bound within the tissues as evidenced by its large volume of distribution (Vd)

The worst case was actually in Washington, DC, from 2001 to 2004, and it was very similar