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Gene profiling studies showed that GHK upregulates the expression of 54 genes known as tumor suppressors while simultaneously downregulating 48 oncogenic genes (Pickart et al., 2018)

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Isoliquiritigenin reduces MDA, Fe2+, and NO levels, while increasing GPX4 and Xct- expression and decreasing NCOA4 expression in an LPS-induced acute kidney injury model in C57BL/6 mice (Tang Y