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The inhibition of HDAC1 expression increases the expression of DUSP1, significantly reduces fibrosis markers, and hinders the phosphorylation of Smad3, thus alleviating UUO-induced renal tubules injury and renal fibrosis (Wang S

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Daidzin inhibits hepatocellular carcinoma survival by interfering with the glycolytic/gluconeogenic pathway through downregulation of TPI1

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GR was shown to drive the expression of a subset of AR target genes necessary for cancer cell survival 156