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uploads/2022/01/HINNAO-Glutathione-D50-Diffusion-Study.pdf 3

In an imiquimod-induced PsO-like mouse model, oral administration of hispidulin significantly alleviated psoriatic symptoms, including scaling, erythema, and skin thickness

Its a bit like a sink where the drain is partially clogged: even a normal flow of water (stress or stimulants) eventually overflows because it cant drain out fast enough