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Alzheimers and Dementia Transl

Inclusion criteria consisted of newly diagnosed, pathologically confirmed epithelial ovarian cancer, an age of 18 years or older, the ability to provide informed consent, willingness to provide access to medical records, undergoing interval or primary debulking surgery at UPMC/HCC, completing a full course (six cycles) of platinum-based chemotherapy at UPMC/HCC and willingness to provide biospecimens for banking purposes

It has been proved to be a more effective inducer of ferroptosis (Larraufie et al., 2015)

Furthermore, T-cell activation is dependent on Cys, which is supplied to T-cells by the Xc- system, and overexpression of FSP1 or GPX4 protects CD8 + T-cells from ferroptosis (50, 51)

In the case of the o -VA radical, a significant increase in the ability of the carbonyl group and the atom with an unpaired electron toward electrophilic interactions is observed