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Many natural products, including angelica sinensis polysaccharide, ginsenoside Rh4, poncirin, alantolactone and paeonol are potential apoptosis-inducing drugs as an important strategy for the treatment of BC [157,158,159,160,161]

Rhodiola has been demonstrated to enhance BDNF levels and activate the ERK/CREB signaling pathway (12), thereby facilitating neuronal survival and promoting neurogenesis within the hippocampus