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Brady RD, Grills BL, Schuijers JA, Ward AR, Tonkin BA, Walsh NC, et al

Thirty years of preclinical data, a mechanism that makes biological sense, and early human signals that are encouraging this is not a fringe or pseudoscientific compound

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For years, longevity researchers and biohackers have praised NAD+ therapy as the most effective way to restore declining NAD levels, and they arent wrong

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However, in view of the excellent safety profile of B12, even at high doses, supplementation, ideally as part of a more comprehensive nutritional programme, may still be of value when the clinical picture and/or other factors (e.g