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doi: 10.1038/s41586-019-1263-7 20 YangZFujiiHMohanSVGoronzyJJWeyandCM

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The extremely slow and variable activity of dihydrofolate reductase in human liver

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Effect of vitamin D on cognitive decline: results from two ancillary studies of the VITAL randomized trial

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A second concern is dose-titration complexity

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doi:10.1016/S2213-8587(21)00269-2

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