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Furthermore, exercise serves to modulate both NO availability and anabolic signaling pathways, thereby amplifying the effects of these amino acids

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J Biol Chem 277, 2694426949

The results suggest that irreversible impairment of the integrity of the cell membrane causes irreversible damage to tubular epithelial cells, the resultant increase in permeability being followed by a decrease in nucleotide content without marked effect on gluconeogenesis or mitochondrial membrane integrity