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doi: 10.1016/j.autrev.2008.08.003 228 HornigMGottschalkGPetersonDLKnoxKKSchultzAFEddyMLet al

Glutathione contains anti-inflammatory properties

HCQ-induced cardiac toxicity after high oral doses was remarkable, while no cardiac adverse effect or significant electrocardiogram (ECG) changes were reported after administration of nebulized inhaled HCQ simple solution to healthy volunteers with 40-fold lower dose for COVID-19 treatment [43]

This redox imbalance ultimately leads to severe damage to membrane lipids, dysfunction and death of alveolar epithelial and vascular endothelial cells, and consequent lung tissue injury and respiratory impairment

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