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3.3 Role of Vit D in innate immunity in MS The role of Vit D in the pathogenesis of MS could be more clearly understood by breaking it down into three distinct steps: (i) activation of autoreactive B and T-cells, (ii) disruption of BBB by autoreactive cells and infiltration into the CNS, (iii) effector function of infiltrated cells and progressive neurodegeneration (102)

96, 229240 10.1016/0165-3806(96)00117-4 [DOI] [PubMed] [Google Scholar] Knott G