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In this study, we investigated the regulation of the TSS pathway in SCD erythroblasts under hypoxia and excess hemin exposure conditions

(Pececnik et al., 2025) These are genuinely interesting mechanistic observations

This upregulation of the GH receptor potentiated the proliferative effects of growth hormone, as evidenced by increased cell proliferation (MTT assay) and proliferating cell nuclear antigen (PCNA) expression

BPC-157 acts predominantly through angiogenic and growth-factor receptor pathways, including VEGFR2 upregulation, FAK-paxillin pathway activation, and eNOS-driven vascular effects