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Dose adjustments as needed

53,54 The identification and measurement of estrogens is no longer performed by traditional biological assays

Problems arise when this intricate dance goes awry

10.1177/1934578x1100600923 61 JiangZ

Due to the conformational differences between the P72 and R72 missense mutants, we speculated that their propensity for rescue by p53 targeting drugs, such as APR-246, may differ in that mutants with the P72 SNP would exhibit increased sensitivity