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Saotome M, Katoh H, Yaguchi Y, Tanaka T, Urushida T, Satoh H, et al

Consuming excess vitamin B9, known as folate or folic acid, can impact mental function as it can hide symptoms of vitamin B12 deficiency until neurological effects become irreversible

Given the extent of DLPFC damage often seen in sTBI, neither agent alone may be sufficient, but their combination likely yields a synergistic therapeutic effect

[DOI] [PubMed] [Google Scholar] [56].Boschetti E, Advanced sorbents for preparative protein separation purposes, J

It is catalyzed by betaine-homocysteine methyltransferase (BHMT)

In particular, a highly selective small-molecule NIK inhibitor, SMI1, has been shown to effectively ameliorate disease symptoms in animal models of SLE, improving survival, reducing renal pathology, decreasing proteinuria scores [113]