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doi: 10.1001/jama.2024.6542 347 HercbergSGalanPPreziosiPBertraisSMennenLMalvyDet al

The number of macroscopic nodules was then recorded

In vitro hepatic models suggested that flavonoids and sulfur-containing compounds in garlic supplements might interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistance protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability

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Bertinato J, Iskandar M, LAbb MR

This leads to an increase in the activity of the glutathione-dependent enzymes, glutathione reductase and glutamate-cysteine ligase, and the glutamate/cystine antiporter, which are critical in the production of reduced glutathione, which plays a vital role in neutralizing ROS (Lee et al., 2003