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p62 is a key regulator of nutrient sensing in the mTORC1 pathway

This systematic review of data on disability-associated outcomes for all forms of schistosomiasis shows that the disease is significantly associated with anaemia, chronic pain, diarrhoea, exercise intolerance and undernutrition, suggesting that the disability burden previously assigned to schistosomiasis by the WHO is an underestimate and indicating a need to reassess priorities for treating this silent pandemic

Our results thus indicated that AITC treatment led to glutathione depletion which contributed to the higher susceptibility of glutathione mutants, but the molecular mechanism behind this physiological response is likely more complicated