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doi: 10.1089/vbz.2017.2133 [DOI] [PubMed] [Google Scholar] 306

25,26 BMAL1 is the core of the circadian rhythm

The fixed cells were then incubated at -20 C overnight

Berberine ameliorates metabolic-associated fatty liver disease mediated metabolism disorder and redox homeostasis by upregulating clock genes: Clock and Bmal1 expressions

10.4103/0973-7847.194044 13 AnandhanA.DodsonM.ShakyaA.ChenJ.LiuP.WeiY.et al (2023)

A healthy liver processes about one standard drink per hour, but liver damage or disease can impair this function, making it easier for alcohol to accumulate in the bloodstream