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These features were used for subsequent clustering (Fig.6 b) and PCA (Fig.6 c) analyses

Molecules 26(9):2506 Seely D, Wu P, Fritz H, Kennedy DA, Tsui T, Seely AJ, Mills E (2012) Melatonin as adjuvant cancer care with and without chemotherapy: a systematic review and meta-analysis of randomized trials

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Additionally, very few studies include comprehensive pharmacokinetic assessments or tissue distribution analyses, which are essential for determining whether therapeutically relevant concentrations are achieved in gastric tissue

For younger, healthier, lighter individuals, titration runs cautiously pushing past the efficacious dose tends to bring on undesirable side effects