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Alternatively, P53 enhances the sensitivity of cells to ferroptosis by enhancing the expression of spermidine/spermine N1-acetyltransferase 1 (SAT1) and glutaminase 2 (GLS2) and inhibiting cystine uptake [101,102,103]

We conclude by outlining important knowledge gaps and discussing areas requiring future research

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For the lung IL-5 mainly acts systemically to induce eosinophilia, whilst IL-4/13-induced eotaxin promotes the transmigration of eosinophils across the vascular bed into the pulmonary tissue