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For instance, antioxidants have been shown to protect zebrafish lateral-line hair cells from ototoxic damage, and mitochondrial transplantation, a novel form of therapy, enhances bioenergetics and mitigates oxidative stress-induced apoptosis in auditory cells (Holmgren and Sheets, 2020

Interestingly, this one skews toward no-DAC, especially with pre-bed dosing

Lipid peroxidation products such as oxidized phosphatidylethanolamine (PEox) generate hydroxyl radicals through the Fenton reaction, which directly damage cell membrane integrity and release toxic aldehydes (such as malondialdehyde, MDA) (172)

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This dependency on keton is particularly crucial for the developing brain of preterm infants