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Nitric Oxide Pathway Studies Nitric oxide (NO) is a gas molecule that the bodys cells naturally produce

doi: 10.1016/j.oneear.2024.04.006

Physicians India 54 , 775782 (2006)

The resulting downregulation of JMJD3 leads to suppressed EDNRB expression and compensatory upregulation of EDNRA, promoting endothelin-mediated vasoconstriction, ERK pathway activation, and vascular remodelingall key features of hypertension [55,56,57]